Putting Patients with Ulcerative Colitis on the Right Treatment Path

Treatment selection for ulcerative colitis (UC) is largely based on disease severity and prognosis: patients with mild UC often achieve remission with 5-aminosalicylates, whereas patients with active disease often require corticosteroids. Though effective for managing flares and inducing remission, prolonged steroid use leads to serious side effects. Fortunately, the search for steroid-sparing UC treatments has, in the last decade, led to the development of biologics and small-molecule inhibitors that target specific immune pathways involved in UC. These options provide new hope for many UC patients but have complicated the process of treatment selection for clinicians, leading to variations in practice and substandard outcomes. Guidelines from the American Gastroenterological Association and the American College of Gastroenterology outline evidence-based medication choices and emphasize the importance of patient preferences in the treatment-selection process; nevertheless, less than 50% of gastroenterologists participate in shared decision-making with their patients.

This interactive activity provides points of view from doctors and patients on the issues they confront as they face UC—issues like steroid use, treatment plans, medication adherence, and general day-to-day living with UC. Each point of view is followed by a brief discussion that will help gastroenterologists incorporate steroid-sparing therapies using small-molecule inhibitors and biologics to achieve UC remission, ensure that patients are knowledgeable about the benefits and drawbacks of available treatment options, and improve communication with patients regarding their care.
Educational Partner: RedMedEd

Medium: Interactive Module

Commercial Support: Support for this activity has been provided through educational grants from AbbVie Inc.; Janssen Biotech, Inc., administered by Janssen Scientific Affairs, LLC; and Takeda Pharmaceuticals U.S.A, Inc.

Target Audience

This activity has been designed to meet the educational needs of gastroenterologists and other clinicians who provide care to patients with UC.

Learning Objectives

After completing this activity, participants will be able to:

  • Design individualized treatment plans that incorporate the use of biologics and small-molecule inhibitors to minimize steroid use and to maximize disease remission;
  • Promote improved medication adherence, satisfaction with therapy, and disease outcomes by engaging patients in shared decision-making.
Additional information
ACGME/ABMS Core Competencies: 
Patient Care and Procedural Skills
Medical Knowledge
Interpersonal and Communication Skills
For more information, please contact:
CME Coordinator Contact Name: 
CME Coordinator Contact Email: 
CME Coordinator Contact Phone: 
Available credit: 
  • 1.00 AMA PRA Category 1 Credit™
  • 1.00 Participation
Activity opens: 
Activity expires: 
  David T. Rubin, MD
  Program Chair
  Joseph B. Kirsner Professor of Medicine
  Section Chief, Gastroenterology, Hepatology and Nutrition
  Co-Director, Digestive Diseases Center
  University of Chicago Medicine
                          Chicago, Illinois
  Bincy P. Abraham, MD, MS
  Professor of Clinical Medicine
  Weill-Cornell & Houston Methodist Academic Institute
  Director, Fondren Inflammatory Bowel Disease Program
  Houston Methodist
  Houston, Texas
  Ethan Blumenthal
  Patient Advocate
  Chicago, Illinois


Disclosure Declarations
As a provider accredited by the ACCME, The University of Chicago Pritzker School of Medicine asks everyone in a position to control the content of an education activity to disclose all financial relationships with any ineligible companies. This includes any entity whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients. Financial relationships are relevant if a financial relationship, in any amount, exists between the person in control of content and an ineligible company during the past 24 months, and the content of the education is related to the products of an ineligible company with whom the person has a financial relationship. Mechanisms are in place to identify and mitigate any relevant financial relationships prior to the start of the activity.

Additionally, The University of Chicago Pritzker School of Medicine requires Authors to identify investigational products or off-label uses of products regulated by the US Food and Drug Administration at first mention and where appropriate in the content.

Physician Credit
This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of the University of Chicago Pritzker School of Medicine and RedMedEd. The University of Chicago Pritzker School of Medicine is accredited by the ACCME to provide continuing medical education for physicians.

The University Of Chicago Pritzker School Of Medicine designates this enduring material for a maximum of 1 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

American Board of Internal Medicine MOC II Credit
Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 1 MOC point in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.
Other Healthcare Professions Credit
Nurses and other healthcare professionals will receive a Certificate of Participation. For information on the applicability and acceptance of certificates of participation for educational activities certified for AMA PRA Category 1 Credit™ from organizations accredited by the ACCME, please consult your professional licensing board.
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