Activity Length: 25 minutes
Test Time: 3 minutes
After this activity, participants will be able to:
- Recall the biochemical and pathophysiologic characteristics of Wolfram syndrome;
- Identify which therapies are currently in development for Wolfram syndrome and their mechanism of action;
- Describe the clinical features of Wolfram syndrome.
Commercial Support: This CME-certified activity has not requested or received any support or funding from commercial interests. This includes but is not limited to, pharmaceutical companies and medical device manufacturers.
UNIVERSITY OF CHICAGO FACULTY
Samuel E. Schechter Professor of Medicine
Professor of Medicine and Pathology & Immunology
Division of Endocrinology
Metabolism and Lipid Research
As a provider accredited by the ACCME, The University of Chicago Pritzker School of Medicine asks everyone in a position to control the content of an education activity to disclose all financial relationships with any ineligible companies. This includes any entity whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients. Financial relationships are relevant if a financial relationship, in any amount, exists between the person in control of content and an ineligible company during the past 24 months, and the content of the education is related to the products of an ineligible company with whom the person has a financial relationship. Mechanisms are in place to identify and mitigate any relevant financial relationships prior to the start of the activity.
Additionally, The University of Chicago Pritzker School of Medicine requires Authors to identify investigational products or off-label uses of products regulated by the US Food and Drug Administration at first mention and where appropriate in the content.
Siri Atma Greeley, MD, PhD
Peggy Hasenauer, MS, RN
Lisa Letourneau-Freiberg, MPH, RD, LDN
Rochelle Naylor, MD
Louis Philipson, MD, PhD has received research funding from Novo Nordisk, Dompe, and Protect Bio and has served on the advisory board of Nevro.
Fumihiko Urano, MD, PhD has no relevant relationships with ineligible companies to disclosure. Dr. Urano will discuss the results of the clinical trial of dantrolene sodium in patients with Wolfram syndrome and pre-clinical study results of AMX0035 in Wolfram syndrome models.
The Center for Continuing Medical Education staff have no relevant financial relationships with ineligible companies to disclose.
All of the relevant financial relationships listed for these individuals have been mitigated.
The University of Chicago Pritzker School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.
University of Chicago Medicine is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation.
Participants who successfully complete the entire activity and complete an evaluation form will earn 0.50 contact hours.
Other Healthcare Professional Credit