Learning Objectives:

1. Understand ocular findings associated with mitochondrial systemic disease

2. Understand the characteristic pattern of Mitochondrial maculopathy

3. The shunting of blood from a high-flow arterial system into the low-flow venous system is what produces an increased vascular pressure, which impedes venous drainage, leading to vascular congestion

4.  Classic triad to recognize: pulsatile exophthalmos, intractable orbital pain and bruit and chemosis