Learning Objectives:

1. Discuss the synergistic effects of immunotherapy and radiation therapy

2. Explain the details of the COSINR study

3. Discuss the correlative studies aiming to better understand the tumor microenvironment pre- and post-radiation therapy.  

and

Learning Objectives:

1. Review the current molecular pathogenesis and clinical problem of triple-negative breast cancer. 
2. Discuss the alterations of metabolism that are responsible for the Warburg effect and the role of BACH1 in controlling this process. 
3. Investigate the effect of BACH1 regulation on reactive oxygen species as a potential therapeutic target in triple-negative breast cancer and determine if BACH1 regulation of metabolism is conserved in other forms of malignancy.