Learning Objectives:
- Review definition, prevalence and clinical significance of Clonal Hematopoiesis of Indeterminate Significance (CHIP)
- Discuss the link between TET2 mutated CHIP and bacterial driven systemic inflammation in mice
- Explore the mechanisms underlying the pro-inflammatory dysregulation in TET2 deficient macrophages
- Discuss our endeavor to delineate the role of bacterial driven inflammation in progression from CHIP to hematologic malignancies in humans
and
- To describe current methods non-invasive monitoring for immunotherapy response
- To describe novel, predictive, peripheral biomarkers of immunotherapy response
- To present phase 1 trials testing novel strategies to overcome specific mechanisms of immunotherapy resistance
Session date:
10/22/2018 - 12:00pm to 1:00pm CDT
Location:
UCMC
5841 South Maryland Avenue
MC2115 HemOnc Conference Room E215
Chicago, IL
60637
United States
See map: Google Maps
Add to calendar:
- 1.00 AMA PRA Category 1 Credit™
- 1.00 Participation
Speaker Name:
Dr. Afaf Osman and Dr. Daniel Olson