Bringing together epileptologists, neurosurgeons, neuroradiologists, neuropsychologists, rehabilitation specialists, nurses, trainees, and other members of the multidisciplinary care team, this conference provides a collaborative forum to review complex epilepsy cases and develop individualized treatment strategies. Participants integrate clinical findings, diagnostic testing, neuroimaging, and other relevant data to evaluate candidacy for epilepsy surgery and other advanced therapeutic interventions. Through multidisciplinary case review and the application of current evidence, learners will strengthen clinical decision-making, enhance communication across specialties, and improve the quality, coordination, and outcomes of care for patients with medically refractory epilepsy.