Learning Objectives:

Marilyn Arosemena, M.D.

“The Sleep-Diabetes Relationship:  Sleep Patterns in Maturity-Onset Diabetes of the Young”

Learning Objectives:

1.    Review the sleep-diabetes relationship.

2.    Discuss Maturity Onset Diabetes of the Young (MODY) and its potential role as a group of diabetes caused primarily by metabolic defects without the metabolic insulin-resistance syndrome to better understand the sleep-diabetes relationship.

3.    Discuss results from pilot study and preliminary results from age-gender matched sleep patterns and disorders in MODY.

Sandra Naaman, M.D., Ph.D., FACP

“Identical Dietary Challenge Induces Different Metabolic Responses based on Mealtime and Body Mass Index”

Learning Objectives:

1.    Review orchestration of glucose metabolism over 24-hour period in various BMI groups.

2.    Understand the implications of chrononutrition for weight maintenance and diabetes risk.

Maria Salguero-Bermonth, M.D., M.Sc.

“Advancing Precision Therapeuctics in Monogenic Diabetes”

Learning Objectives:

1.    Evaluate Phenotype, Burden of Care and treatment of patients with HNF1B-MODY.

2.    Describe the Use of SGLT-2 inhibitors in patients with HNF1B-MODY.

3.    Describe the in-utero course, childhood growth trajectory, pubertal timing, insulin sensitivity and appearance of dysglycemia in children with heterozygous mutations in the HNF1A and HNF4A gene.