“10 Year-old Girl with an Overgrowth Disorder”

Presented by:

Susan Tucker, M.D.

Learning Objectives:

      1.    Review potential endocrine manifestations.

      2.   Discuss management considerations.

and

“83 Year-old Woman Presenting with Altered Mental Status and Hypercalcemia”

Presented by:

Laura Dickens, M.D.

Learning Objectives:

      1.    Review presentation of and diagnostic approach to hypercalcemia.

      2.   Discuss management of severe hypercalcemia and evidence for use of loop diuretics.

      3.   Evaluate evidence for vitamin D replacement in primary hyperparathyroidism.

      4.   Review pre-operative localization studies in primary hyperparathyroidism and incidence of ectopic parathyroid adenomas

and

“35 Year-old Woman with a History of Retinoblastoma Presenting with Thyroid Nodules”

Presented by:

Laura Dickens, M.D.

Learning Objectives:

      1.    Discuss the role of RB1 as a tumor-suppressor gene and its contribution to the pathogenesis of retinoblastoma and other malignancies.

      2.   Review ultrasound characteristics of thyroid nodules which increase probability of malignancy.

      3.   Discuss the effects of radiation exposure on the thyroid including risk for thyroid cancer and non-malignant thyroid disease.

      4.   Review the recommendations for monitoring for second malignancies in patients with a history of radiation exposure.