Learning Objectives:

1. Review the pharmacology, pharmacokinetics and adverse events of commonly used sedative and analgesic agents

2. Evaluate key clinical trials that shaped guideline recommendations for the management of analgesia and sedation in the ICU

3. Compare the benefits, safety profiles, and efficacy of propofol and dexmedetomidine for ICU sedation

4. Discuss rapid sequence intubation and nuances of post-intubation sedation requirements

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