Goals and Objectives:

1.Approach the child with FUO + pancytopenia + transaminitis, including when to escalate to bone marrow biopsy and MAS/HLH screening
2.Distinguish hemophagocytic/macrophage-activation-like syndromes from infectious, oncologic, and rheumatologic mimics
3.Understand the diagnostic value and limits of biomarkers like ferritin, LDH, CXCL9, and autoantibodies (anti-Smith, anti-RNP)
4.Justify empiric immunomodulatory therapy (IL-1 blockade, steroids) before a unifying diagnosis is reached
5.Recognize that complex inflammatory presentations often remain undifferentiated at discharge
Session date: 
09/29/2026 - 12:00pm to 1:30pm CDT
Location: 
Comer Children's Hospital
5721 S. Maryland Ave
Rm K155
Chicago, IL 60637
United States
See map: Google Maps
Add to calendar: 
  • 1.00 AMA PRA Category 1 Credit™
  • 1.00 Participation
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Speaker Name: 
Dr. Alyssa Kalsbeek