Bringing together neurologists, neurosurgeons, oncologists, radiologists, pathologists, and other members of the multidisciplinary care team, this weekly conference provides a collaborative forum to review complex neuro-oncology cases and develop individualized, evidence-based treatment strategies. Participants integrate clinical, imaging, and pathologic findings, discuss evolving approaches to the diagnosis and management of primary and metastatic central nervous system tumors, and draw upon the expertise of multiple specialties to optimize patient care. Through multidisciplinary case review and the application of current evidence, learners will strengthen their clinical decision-making, enhance interdisciplinary collaboration, and improve the quality and coordination of care for patients with neuro-oncologic disease.