DESCRIPTION:
This presentation will review translational research and the development of targeted therapies for MLL-rearranged leukemia and NPM1 mutant leukemia
LEARNING OBJECTIVES
• Understand the role of MLL gene rearrangements and NPM1 mutations in the pathogenesis of acute leukemia.
• Discuss preclinical models of MLL-r and NPM1m leukemia and their role in the development of targeted therapies.
• Review the development of MLL-menin inhibitors as targeted therapies for acute leukemia and analyze mechanisms of resistance.

Session date: 
09/08/2025 - 12:00pm to 1:00pm CDT
Add to calendar: 
  • 1.00 AMA PRA Category 1 Credit™
  • 1.00 Participation
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Speaker Name: 
Dr. Michael Thirman